GLP-1 weight-loss drugs put $73 billion in global food value at risk, according to a new report from Brand Finance.

PepsiCo's Lay's ranks as the most exposed food brand in the analysis. Doritos, Hershey's, Cheetos, Kellogg's and Reese's also face significant vulnerability as appetite-suppressing medications reshape consumer eating habits.

The findings land squarely on the snacking and confectionery categories that dominate grocery center aisles. Lay's, Doritos and Cheetos all sit in PepsiCo's Frito-Lay portfolio, meaning one parent company carries concentrated exposure across multiple leading brands. Hershey's and Reese's extend that risk into chocolate, while Kellogg's anchors it in traditional packaged breakfast and snack foods.

For marketers, the $73 billion figure quantifies a threat that has so far been discussed mostly in qualitative terms. Brand Finance, a brand valuation consultancy, attached a hard number to the value at stake across the global food sector.

The report's brand-level detail gives CPG marketers a roadmap for where the pressure concentrates. The most exposed names share a profile: they are heavily reliant on impulse snacking occasions and indulgent formats — precisely the consumption moments GLP-1 users report cutting back on most.

Portfolios stacked with vulnerable brands face a strategic choice. PepsiCo, with three of the six named brands, has the largest single-company exposure in the ranking. Hershey carries two of the six through its eponymous brand and Reese's.

The valuation risk comes as GLP-1 adoption continues to climb, giving the report's scenario weight beyond a hypothetical exercise. Brand Finance's framework suggests the erosion would come through reduced purchase frequency and weakened brand equity rather than a single shock event.

Brands outside the exposed list have an opening. Marketers of protein-forward, portion-controlled and satiety-positioned products can capture share from the snacking giants as GLP-1 users rebalance their baskets.

The next test will be whether exposed brands reposition — through reformulation, portfolio diversification or demand shifting — before the $73 billion in at-risk value shows up in reported sales.